On occasion, we are asked to help customers with special dispensing requirements – something which can’t be done with off-the-shelf equipment.
The Nuffield Department of Clinical Laboratory Sciences at the John Radcliffe Hospital, Oxford were working on the generation of nonviral gene therapy formulations. They wanted a reproducible method to mix the materials from twin barrelled plastic syringes through a static mixing nozzle. We were delighted to get involved. The project has been written up in the journal BioTechniques. Called the LMD 2, the unit is a success.
In summary, we have developed a simple, practical mixing device that offers significant improvements over current production methodologies. The LMD 2 is quick, easy to use with a wide variety of reagents, and directly scalable for the production of formulations in the laboratory or in the clinic.